Open-genre = concept ideas are not limited to 1 genre, like fantasy, sci fi, etc. Just because I am more familiar with it, I will use Pathfinder like we did with SW. Use PF stats and simply re-skin them into to anything you want, without mechanical changes. Matt's nano-bot Summoner is a great example - remember, they don't speak droid just because you re-skin them as droids.
System = PF for character creation, with re-skin ability. I will also include many of the 5e elements, as long as they don't cause conflict with PF. The main ones I am looking at:
Combat - movement + standard action can be broken up and in any order (eliminates need for Shot on the Run\Spring attack tree, though you could still take Dodge)
Actions - quick draw, quick sheath, are all free actions when combined with a move or standard, like in 5e (eliminates many feats)
+ Dex damage to ranged weapons (including guns), but otherwise use PF gun damage codes (lower than SW)
Level - probably somewhere in the middle to start, maybe around 8-10th
I hadn't heard anyone else talk about what's next, after Matt's game. I am in no rush to start, but I want to start putting down ideas.
Feel free to ask questions here